Table 4 Any symptoms ever likely related to Fabry disease of 44 women
From: Pregnancy outcomes of Fabry disease in Austria (PROFABIA)-a retrospective cohort-study
All women (n = 44) | With pregnancy (n = 32) | Without pregnancy (n = 12) | |
|---|---|---|---|
Women with symptoms | 38 (86.4) | 28 (87.5) | 10 (83.4) |
Women without symptomsa | 6 (13.7) | 4 (12.5) | 2 (16.7) |
Age at study entry | 44 (30, 51) | 48 (39, 54) | 24 (21, 32) |
Hypohidrosis, cold or heat intolerance | 21 (47.7) | 15 (46.9) | 6 (50.0) |
Acroparesthesia | 25 (56.8) | 17 (53.1) | 8 (66.7) |
Pain | 23 (52.3) | 17 (53.1) | 6 (50.0) |
Angiokeratomas | 8 (18.2) | 6 (18.8) | 2 (16.7) |
Neurologic symptoms | 10 (22.7) | 9 (28.1) | 1 (8.3) |
Cerebrovascular event | 3 (6.8) | 2 (6.3) | 1 (8.3) |
Cardiac symptoms | 15 (34.1) | 14 (43.8) | 1 (8.3) |
Angina | 8 (18.2) | 8 (25.0) | 0 |
Kidney disease | 11 (25.0) | 11 (34.4) | 0 |
Proteinuria | 15 (34.1) | 12 (37.5) | 3 (25.0) |
Hypertension | 12 (27.3) | 12 (37.5) | 0 |
Gastrointestinal symptoms | 22 (50.0) | 16 (50.0) | 6 (50.0) |
Asthma/COPD | 11 (25.0) | 11 (34.4) | 0 |
Anxiety disorder | 7 (15.9) | 6 (18.8) | 1 (8.3) |
Depression | 16 (36.4) | 14 (43.8) | 2 (16.7) |
Hypacusis | 9 (20.5) | 8 (25.0) | 1 (8.3) |
Tinnitus | 10 (22.7) | 10 (31.3) | 0 |
Vertigo | 14 (31.8) | 12 (37.5) | 2 (16.7) |
Cornea veticillata | 8 (18.2) | 5 (15.6) | 3 (25.0) |
Other | 7 (15.9) | 6 (18.8) | 1 (8.3) |