Table 3 First symptoms likely related to Fabry disease of 44 women
From: Pregnancy outcomes of Fabry disease in Austria (PROFABIA)-a retrospective cohort-study
All women (n = 44) | With pregnancy (n = 32) | Without pregnancy (n = 12) | |
|---|---|---|---|
Age at onset | 11 (6, 20) | 11 (7, 19) | 14 (6, 21) |
Hypohidrosis, cold or heat intolerance | 4 (9.1) | 4 (12.5) | 0 |
Acroparesthesia | 13 (29.5) | 8 (25.0) | 5 (41.7) |
Pain | 14 (31.8) | 12 (37.5) | 2 (16.7) |
Angiokeratomas | 1 (2.3) | 1 (3.1) | 0 |
Neurologic symptoms | 5 (11.4) | 5 (15.6) | 0 |
Cerebrovascular event | 2 (4.5) | 2 (6.3) | 0 |
Cardiac disease | 5 (11.4) | 5 (15.6) | 0 |
Angina | 0 | 0 | 0 |
Kidney disease | 0 | 0 | 0 |
Proteinuria | 2 (4.5) | 0 | 2 (16.7) |
Hypertension | 0 | 0 | 0 |
Gastrointestinal symptoms | 8 (18.2) | 6 (18.8) | 2 (16.7) |
Asthma/COPD | 1 (2.3) | 1 (3.1) | 0 |
Anxiety disorder | 0 | 0 | 0 |
Depression | 0 | 0 | 0 |
Hypacusis | 0 | 0 | 0 |
Tinnitus | 0 | 0 | 0 |
Vertigo | 1 (2.3) | 1 (3.1) | 0 |
Cornea verticillata | 2 (4.5) | 1 (3.1) | 1 (8.3) |
Other | 2 (4.5) | 2 (6.3) | 0 |