Table 1 Characteristics of 44 study participants
From: Pregnancy outcomes of Fabry disease in Austria (PROFABIA)-a retrospective cohort-study
No. of women with Fabry disease | 44 |
No. of families | 28 |
Index case | 15 |
Diagnosis by family screening | 29 |
Ethnicity | |
Caucasian | 43 (97.7) |
Asian | 1 (2.3) |
BMI, kg/m2 | 24 (22, 27) |
Systolic blood pressure, mmHg | 120 (110, 120) |
Diastolic blood pressure, mmHg | 80 (70, 80) |
Hypertension, yes | 9 (20.5) |
Serum creatinine, mg/dl (n = 30) | 0.8 (0.7, 0.8) |
Urinary albumin to creatinine ratio, mg/g (n = 29) | 23 (8, 59) |
Urinary protein to creatinine ratio, mg/g (n = 29) | 106 (60, 177) |
Chronic kidney disease (including one kidney transplant recipient) | 11 (25.0) |
Age at first symptoms, years | 11 (6, 20) |
Age at diagnosis of Fabry disease, years | 34 (21, 47) |
Age at start of treatment (n = 21), years | 46 (32, 51) |
Age at study entry, years | 44 (30, 51) |
Fabry disease specific therapy | 19 (43.2) |
Current enzyme replacement therapy | 16 (36.4) |
Current chaperone therapy | 3 (6.8) |
History of pregnancies | 32 (72.7) |