Table 5 Patient characteristics
Study number | 16 | 17 | 19 | 23 | 28 | 34 | 44 | 45 | 49 | 70 | 71 | 73 |
Language | English | Dutch | Dutch | Dutch | English | English | English | French (English) | Dutch | English | English | English |
Country | Australia | The Netherlands | The Netherlands | Belgium | USA | USA | Canada | France | Belgium | USA | Canada | USA |
Age | 10y 8m | 16y 11m | 10y 4m | 7y 7m | 14y 5m | 15y 8m | 18y 9m | 11y 10m | 12y 0m | 12y 2m | 21y 0m | 12y 7m |
Age of diagnosis | 13 weeks | 5m | 17m | 5y 2m | 12m | 12m | Prenatal | 3m | 3 days | 10 days | 2m | 4 days |
Biological sex | Female | Male | Female | Male | Male | Female | Male | Female | Male | Female | Female | Male |
Epilepsy | No | No | Yes | Yes | Yes | No | No | No | No | Yes | Yes | Yes |
Medication (dose of Benzoate and DMP in mg/Kg/day) | benzoate (275) fluoxetine mirtazapine | benzoate (428) | benzoate (285) | benzoate (294) DMP (4.12) folic acid (co-factor) | benzoate (238) DMP (0.6) | benzoate (250) | benzoate (367) DMP (2.5) clonidine lisdexamp guanfacine fluoxetine lansoprazol | benzoate (450) DMP (7.5) pyridoxal-phosphate haloperidol esomeprazol magnesium carnitine | benzoate | benzoate (258) oxcarbazepine | benzoate (388) DMP(5.2) fluoxetine lansoprazol levonorgestrel, ethinyl estradiol | benzoate (303) DMP (8.7) |
Glycine (µmol/L) | 700 | 368 | 428 | 292 | 402 | 526 | 240 | 285 | 275 | 360 | 242 | 458 |
IQ or DQ With level of ID | Parent reports “Mild/moderate ID, thinks TIQ around 50” | WPPSI TIQ = 40 Moderate | Parent does not know | NONE | Test unknown TIQ = 43 Moderate | Parent does not know | Stanfort-Binet "Moderate" | NONE | DQ = 60 Mild | NONE | Result unknown to author | NONE |