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Table 2 Summary of the results of the behavioral, cognitive, communication, and motor related questionnaires

From: The behavioral phenotype of children and adolescents with attenuated non-ketotic hyperglycinemia, intermediate to good subtype

Study number

 

16

17

19

23

28

34

44

45

49

70

71

73

Biological sex

 

Female

Male

Female

Male

Male

Female

Male

Female

Male

Female

Female

Male

DBC

TPS

68 (P75-90)

15 (< P50)

52 (P75-90)

47 (P50-75)

58 (P75-90)

40 (P50-75)

61 (P75-90)

83 (P90-95)

31 (P50-75)

41 (P50-75)

57 (P75-90)

54 (P75)

Disruptive

24 (P75-90)

3 (< P50)

22 (P75-90)

18 (P50-75)

22 (P75-90)

16 (P50-75)

30 (> P95)

31 (P95)

7 (< P50)

14 (P50-75)

18 (P50-75)

12 (< P50)

Self-absorbed

23 (P90-95)

5 (< P50)

13 (P50-75)

15 (P50-75)

21 (P90-95)

3 (< P50)

13 (P50-75)

30 (> P95)

9 (P75)

20 (P75-90)

20 (P75-90)

28 (> P95)

Comm. Dist.

10 (P90)

2 (< P50)

9 (P75-90)

7 (P50-75)

8 (P75)

6 (P50-75)

7 (P50-75)

8 (P75)

5 (P75)

4 (< P50)

6 (P50-75)

4 (< P50)

Anxiety

7 (P50-75)

2 (< P50)

6 (P75)

4 (P50)

4 (< P50)

9 (P75-90)

6 (P50-75)

11 (P95)

5 (P75-90)

0 (< P50)

6 (P50-75)

4 (< P50)

Social relating

2 (< P50)

0 (< P50)

4 (P50-75)

3 (P50)

1 (< P50)

6 (P50-75)

3 (< P50)

3 (P50-75)

3 (P50-75)

5 (P50-75)

3 (< P50)

5 (P50-75)

SCQ

Total score

17

11

25

22

19

7

27

20

13

13

14

15

Current

10

6

15

7

14

7

15

9

13

10

11

14

ABAS

GAC

61 (P0.5 – EL)

61 (P0.5 – EL)

< 55 (< P0.1 –EL)

56 (P0.2 – EL)

56 (P0.2 – EL)

76 (P5 – L)

67 (P1 – EL)

61 (P0.5 – EL)

62 (P0.6 – EL)

47 (< P0.1 –EL)

60 (P0.4 – EL)

47 (< P0.1–EL)

Conceptual

57 (P0.2 – EL)

57 (P0.2 – EL)

< 55 (< P0.1 –EL)

< 55 (< P0.1 –EL)

56 (P0.2 – EL)

73 (P4 – L)

69 (P2 – EL)

62 (P0.6 – EL)

55 (< P0.1 –EL)

49 (< P0.1 –EL)

62 (P1 – EL)

49 (< P0.1–EL)

Practical

56 (P0.2 – EL)

60 (P0.4 – EL)

58 (P0.3 – EL)

64 (P0.8 – EL)

68 (P2 – EL)

82 (P12 – BA)

64 (P1 – EL)

60 (P0.4 – EL)

67 (P1.4 – EL)

48 (< P0.1 –EL)

59 (P0.3 – EL)

48 (< P0.1–EL)

Social

86 (P18 – BA)

83 (P12.9 – L)

57 (P0.2 – EL)

57 (P0.2 – EL)

56 (P0.2 – EL)

79 (P8 – L)

77 (P6 – L)

77 (P6.3 – L)

75 (P4.8 – L)

54 (P0.1 –EL)

70 (P2 – EL)

54 (P0.1–EL)

CCC-2

Scales ≥ P95 (n)

7/10

4/10

10/10

///

7/10

3/10

9/10

5/10

Non-valid

///

7/10

///

GCC

> P99

> P99

> P99

> P99

P90-95

> P99

P95-98

> P99

Pragm. Score

P98

P90-95

> P99

P95-98

P80

P99

P90-95

P95-98

SIDI

P2-5

P2

P15-20

P2-5

P2-5

P30

P15

P10-15

Soc.Rel scale

Average

Average

Very weak

Average

Average

Average

Weak

Average

MSC

Total

87

36

64

71

46

41

50

90

47

69

68

109

Age equivalent

< 36m

65-66m

41-42m

38m

54m

59m

51m

< 36m

53m

38-39m

39m

< 36m

DCDDaily (i.e.5y)

Participation

68 (≥ P95)

31 (< P85 ~7-8y)

63 (≥ P95)

55 (≥ P95)

42 (< P85 ~6y)

45 (< P85)

36 (< P85 ~7-8y)

44 (< P85)

41 (< P85~6y)

67 (≥ P95)

52 (≥ P95)

Non-valid

Quality

63 (≥ P95)

31 (< P85 ~7-8y)

52 (≥ P95)

58 (≥ P95)

48 (≥ P95)

39 (P85-95~5-6y)

44 (≥ P95)

65 (≥ P95)

35 (< P85 ~6y)

56 (≥ P95)

57 (≥ P95)

Acquisition

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

≥ P95

M-ABC

TMS (age)

50 (< 5y)

9 (5y)

34 (< 5y)

37 (< 5y)

19 (6y)

21 (5y)

21 (5y)

60 (< 5y)

16 (5y)

32 (5y)

53 (< 5y)

Non-valid

Section C (n/13)

7

5

5

4

8

11

10

4

10

5

10

6

Probl acc parent

Yes

Yes

No

Yes

No

No

Yes

Yes

Yes

No

Yes

Yes

ADHD

~ DBC (n/9)

8

4

8

7

7

5

7

9

6

8

8

6

~M-ABC (n/5)

5

1

4

3

5

5

4

3

4

4

4

4

  1. Abbreviations: TPS Total Problem Score, P Percentile, Comm. Dist. Communication disturbance, GAC General Adaptive Composite, EL Extremely low, L Low, BA Below average, n Number, GCC General Communication Composite, Pragm. Score Pragmatic score, SIDI Social Interaction Difference Index, m month, y year, TMS Total Motor Score, Probl. Acc. Parent Problem in motor functioning according to parents