Fig. 4From: Identification and characterization of a new pathologic mutation in a large Leber hereditary optic neuropathy pedigreePhenotypic results from the study of negative control (Oc, white), positive control (O3460, red), and mutant (O3734, green) cybrids. a Levels of different protein subunits from oxidative phosphorylation (OXPHOS) complexes (in brackets) (N = 3). Picture of a Western blot immunodetection and quantitative graphic. M, molecular weight marker. b Citrate synthase specific activities (N = 3). c Oxygen consumption in cybrids exposed to growing concentrations of capsaicin. Means and standard deviations are shown (N = 4). Hashtags (#) and asterisks (*) indicate statistically significant differences (p < 0.050) versus the same cybrid without capsaicin and the negative control cybrid (Oc) at the same capsaicin concentration, respectivelyBack to article page