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Table 2 Baseline Comorbidities, 1 year before Surgery

From: Economic burden of patients with post-surgical chronic and transient hypoparathyroidism in the United States examined using insurance claims data

 

cHP Cohort

N = 1,069a

tHP Cohort

N = 773

Cardiovascular and metabolic disorders

Arrhythmias

195 (18.2%)

113 (14.6%)

Congestive heart failure

60 (5.6%)

33 (4.3%)

Diabetes

225 (21.0%)

175 (22.6%)

Hypertension

485 (45.4%)

331 (42.8%)

Central Nervous System

Basal ganglia calcification

0 (0.0%)

0 (0.0%)

Peripheral Neuropathy

25 (2.3%)

9 (1.2%)

Seizures and convulsions

21 (2.0%)

10 (1.3%)

Laboratory Imbalances

Hypercalcemia

142 (13.3%)

144 (18.6%)

Hypercalciuria

9 (0.8%)

5 (0.6%)

Hypocalcemia

77 (7.2%)

8 (1.0%)

Malignancy

Any Malignancy

457 (42.8%)

265 (34.3%)

Thyroid Cancer

379 (35.5%)

212 (27.4%)

Musculoskeletal

Fractures

32 (3.0%)

19 (2.5%)

Osteoporosis

95 (8.9%)

50 (6.5%)

Neuropsychiatric

Anxiety

236 (22.1%)

165 (21.3%)

Cognitive impairment

27 (2.5%)

15 (1.9%)

Dementia

10 (0.9%)

6 (0.8%)

Depressive disorders

202 (18.9%)

135 (17.5)

Sleep-wake disorders

190 (17.8%)

115 (14.9%)

Other

Cataract formation

0 (0.0%)

0 (0.0%)

Tetany

2 (0.2%)

1 (0.1%)

Renal Disease

CKD (Stage 1–4, unspecified)

87 (8.1%)

54 (7.0%)

CKD Stage 5, ESRD and failure

44 (4.1%)

31 (4.0%)

Diabetic Nephropathy

87 (8.1%)

59 (7.6%)

Nephrolithiasis/renal stones

65 (6.1%)

54 (7.0%)

  1. aComorbidities are based on claims from the 1-year pre-index period and not all patients had a full 1-year of data
  2. CHF: Congestive Heart Failure; cHP: Chronic Hypoparathyroidism; CKD: Chronic Kidney Disease; CNS: Central Nervous System; ESRD: End Stage Renal Disease; tHP: Transient Hypoparathyroidism