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Table 4 Comparation of the occurrence of carriers among false-positive and negative newborns

From: Abnormal biochemical indicators of neonatal inherited metabolic disease in carriers

 

Case

Carriers

Non-carriers

P

Congenital hypothyroidism

    

false-positive

2

0

2

negative

686

58

628

 

Organic acid metabolic disease

    

false-positive

99

12 (12.12%)

87(87.87%)

0.096

negative

686

50 (7.29%)

636(92.71%)

 

Amino acid metabolic disease

    

false-positive

58

9 (15.52%)

49(84.48%)

0.030

negative

686

46 (6.71%)

640(93.29%)

 

Fatty acid β oxidation disorder

    

false-positive

53

15 (28.30%)

38(71.70%)

< 0.001

negative

686

50 (7.29%)

636(92.71%)

 
  1. Note: Carriers (or non-carriers) in this table refer to the number of carriers (or non-carriers) in false positive and negative newborns, which is different from the carrier group and non-carrier group in Table 3.