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Table 2 Logistic regression results

From: GBA1 as a risk gene for osteoporosis in the specific populations and its role in the development of Gaucher disease

 

Overall (N = 64,057)

Male (N = 21,823)

Female (N = 42,234)

OR

95% CI

P value

OR

95% CI

P value

OR

95% CI

P value

Age (year)

1.12

(1.11, 1.12)

 < 0.001*

1.07

(1.06, 1.07)

 < 0.001*

1.13

(1.12, 1.14)

 < 0.001*

Gender

0.66

(0.62, 0.71)

 < 0.001*

BMI (kg/m2)

0.91

(0.91, 0.92)

 < 0.001*

0.92

(0.91, 0.94)

 < 0.001*

0.89

(0.88, 0.9)

 < 0.001*

Smoking

1.16

(1.09, 1.24)

 < 0.001*

1.34

(1.23, 1.45)

 < 0.001*

Sport Habit

0.68

(0.64, 0.72)

 < 0.001*

0.64

(0.59, 0.69)

 < 0.001*

0.68

(0.63, 0.73)

 < 0.001*

Menopause

2.87

(2.53, 3.26)

 < 0.001*

eGFR (mL/min/1.73m2)

1.01

(1.01, 1.01)

 < 0.001*

1.01

(1.01, 1.01)

 < 0.001*

1.01

(1.01, 1.02)

 < 0.001*

rs11264345

1.06

(1.02, 1.11)

0.002*

1.10

(1.04, 1.17)

0.002*

1.03

(0.98, 1.08)

0.270

  1. OR odds ratio, CI confidence interval, eGFR estimated glomerular filtration rate
  2. *Represent P value less than 0.05