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Table 2 Comparison of laboratory values at the onset of treatment and at present

From: Adherence to medical treatment for Wilson’s disease in children and adolescents: a cohort study from Turkey

Parameters

Onset of treatment

At present

P value

ALT, UI/L, median (range)

164.5 (26–1778)

45.5 (12–299)

< 0.001

AST, UI/L, median (range)

87 (26–348)

37.5 (12–199)

< 0.001

GGT, UI/L, median (range)

50 (14–277)

26 (11–92)

0.007

ALP, UI/L, median (range)

285.5 (74–488)

237.5 (44–439)

0.014

Total bilirubin, mg/dL, median (range)

0.46 (0.19–5.80)

0.65 (0.26–1.84)

0.048

Direct bilirubin, mg/dL, median (range)

0.85 (0.01–2.04)

0.14 (0.06–0.98)

0.157

Albumin, g/dL, median (range)

4.43 (1.22–5.03)

4.38 (3.76–5.40)

0.510

INR, median (range)

1.14 (0.97–4.77)

1.01 (0.92–1.22)

< 0.001

Urinary copper, µg/24 h, median (range)

113.0 (5.0-618.0)

288.6 (0.97-1793.37)

0.018

  1. ALT: Alanine transaminase, AST: Aspartate aminotransferase, GGT: Gamma-glutamyl transferase, ALP: Alkaline phosphatase, INR: International normalized ratio, Boldface font indicates statistically significant variable (p < 0.05)