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Table 1 Participant characteristics, intervention history, and behavioral functioning

From: Neurobehavioral and developmental profiles: genotype–phenotype correlations in individuals with Cornelia de Lange syndrome

 

NIPBL (N = 26)

SMC1A (N = 12)

p Value

Mean (standard deviation)

Sex

10F

6F

n.s

Age (year)

20.46 (11.21)

11.08 (9.04)

F = 6.42, p = 0.016

Race

 White

100%

75%

FET p = 0.026

 Asian

0%

16.7%

 

 Other

0%

8.3%

 

Insurance

 Private/commercial

46.2%

66.7%

n.s

 Medical assistance

34.6%

8.3%

 

 Military

11.5%

16.7%

 

History of self injurious behaviors (% of the sample)

58.3%

0%

FET p = 0.002

History of anxiety (% of the sample)

70.8%

16.7%

FET p = 0.003

Attention total (minimum to maximum score = 0–8)

N = 20, 4.90 (2.38)

N = 10, 5.00 (2.53)

n.s

Repetitive behavior total (minimum to maximum score = 0–8)

N = 22, 2.77 (2.26)

N = 11, 0.81 (1.25)

U = 55.5, p = 0.01

Intervention history (% of sample, participation on a weekly to monthly basis)

 Speech/language therapy

50%

77.8%

n.s

 Occupational therapy

59.1%

80%

n.s

 Physical therapy

45.5%

90%

FET p = 0.04

 Total therapies (minimum of 0, maximum of 3)

1.54 (1.40)

2.40 (1.07)

n.s

Uses communication devices

3.8%

25%

FET p = 0.08

  1. FET Fishers exact test, n.s. not significant results (p > 0.10)
  2. Only respondents who completed all attention and repetitive behavior items were included in the mean average for Attention Total and Repetitive Behavior Total