Orphanet Journal of Rare Diseases

Table 2 Nutritional outcomes in 14 adults with OI undergoing restricted Mediterranean Diet

From: Short-term effects of Mediterranean diet on nutritional status in adults affected by Osteogenesis Imperfecta: a pilot study

	Pre-intervention		Post-intervention		P value
	Mean	SD	Mean	SD	P value
Anthropometric parameters
BW (kg)	43.59	19.80	40.41	18.85	< 0.001
BMI (kg/m²)	30.47	8.09	28.07	7.53	< 0.001
WC (cm)	83.61	18.38	79.61	17.79	< 0.001
NC (cm)	36.52	5.08	34.58	4.63	< 0.001
H/WC	71.88	16.19	68.37	15.61	< 0.001
H/NC	31.62	6.16	29.84	5.32	< 0.001
NC/WC	44.59	5.44	42.47	6.38	0.863
Body Fat (%)	32.92	7.50	29.85	8.44	0.006
AMA (cm²)	33.84	12.01	33.24	9.37	0.607
AFA (cm²)	29.80	16.12	23.07	15.65	0.011
Resting energy expenditure
RQ	0.86	0.05	0.85	0.05	0.149
REE (kcal/kg BW)	27.26	6.04	29.20	7.79	< 0.001
REE/pREE %	99.40	14.97	98.90	15.66	0.651
Blood parameters
Glucose (mg/dL)	86.91	13.17	78.55	15.50	0.003
Uric acid (mg/dL)	4.73	1.02	5.05	1.25	0.107
Urea (mg/dL)	30.64	9.16	29.64	4.78	0.631
Creatinine (mg/dL)	0.39	0.20	0.47	0.20	0.063
TC (mg/dL)	199.45	32.71	184.82	23.59	0.036
HDL-C (mg/dL)	52.00	8.39	58.18	27.45	0.511
TC/HDL	3.91	0.78	3.52	0.90	0.302
LDL-C (mg/dL)	131.55	24.86	119.55	18.84	0.009
TG (mg/dL)	88.91	36.64	87.73	16.70	0.910
GGT	17.64	11.31	15.52	7.04	0.250
AST	19.67	5.29	19.90	5.49	0.805
ALT	20.56	17.33	19.91	12.77	0.762
Vitamin D (ng/mL)	29.19	16.12	30.76	16.05	0.799

BW body weight, BMI Body Mass Index, WC waist circumference, NC neck circumference, H height, AMA arm muscle area, AFA arm fat area, RQ respiratory quotient, REE resting energy expenditure, pREE predicted REE using Harris-Benedict equation, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, TG triglycerides, ALT Alanine Amino Transferase, AST Aspartate Amino Transferase, GGT γ-glutamyl transferase

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ISSN: 1750-1172

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