Table 3 The annualized factor consumption
Patients and subgroups | Total factor consumption (IU/kg/year), median (IQR) | P-value | |
|---|---|---|---|
Before study inclusion | 6 months after the start of the exercise intervention | ||
All patients (N = 13) | 1724.8 (1235.4-1778.5) | 1322.1 (1258.7-1727.6) | 0.008 |
Subgroup by age | |||
≤ 15 years (n = 4) | 1753.0 (1351.0-2078.0) | 1736.3 (1336.5–2028.0) | 0.09 |
> 15 years (n = 9) | 1514.4 (1235.4-1764.7) | 1307.5 (1258.7-1601.6) | 0.02 |
Subgroup by target joints | |||
Present (n = 10) | 1403.6 (1095.3-1764.7) | 1284.6 (1067.8-1601.6) | 0.01 |
Absent (n = 3) | 1778.5 (1727.6-2377.8) | 1745.0 (1727.6-2311.1) | 0.17 |