Fig. 2
From: Clinical and genetic studies for a cohort of patients with congenital stationary night blindness
Representative examples of ERG. The ERG trace is recorded in a normal subject and patients with congenital stationary night blindness (CSNB). In dark-adapted and light-adapted conditions, stimulation with a dim flash led to an almost absent rod-specific response in patients with NYX, GRM6, and TRPM1 variations, CACNA1F variations. In light-adapted conditions, the response to a standard flash (LA 3.0) had abnormal waveforms with broadened a-waves and biphasic oscillatory potentials in patients with NYX, GRM6, and TRPM1 variations. Patients with CACNA1F variation showed substantially reduced a-wave and b-wave amplitude in light-adapted 3.0 and markedly decreased 30-Hz flicker ERG amplitude