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Table 4 Multiple regression analysis of echocardiographic parameters

From: Echocardiographic abnormalities and joint hypermobility in Chinese patients with Osteogenesis imperfecta

 

Dependent variable

Independent variable

AD

LAD

IVST

LVPWT

LVEDd

LVESd

LVEF

FS

LVM

β

P

β

P

β

P

β

P

β

P

β

P

β

P

β

P

β

P

A. In the juvenile group

Age

0.372

<0.001

-0.069

0.660

0.100

0.026

0.149

<0.001

0.161

0.289

0.089

0.446

-0.071

0.633

0.276

0.291

1.715

0.072

Sex

-0.774

0.051

0.397

0.570

-0.009

0.965

-0.033

0.849

-2.222

0.001

-1.471

0.005

0.310

0.640

1.342

0.247

-10.476

0.014

BSA

2.394

0.008

10.987

<0.001

1.277

0.005

0.894

0.026

10.730

<0.001

7.576

<0.001

-1.117

0.453

-5.276

0.046

57.899

<0.001

SBP

0.040

0.094

0.011

0.796

0.011

0.342

-0.008

0.442

-0.009

0.818

-0.035

0.258

0.044

0.276

0.096

0.168

-0.100

0.691

DBP

0.036

0.189

0.039

0.424

0.001

0.944

0.013

0.276

0.025

0.599

0.010

0.787

0.025

0.589

0.044

0.583

0.235

0.420

OI

-0.678

0.159

-3.670

<0.001

-0.043

0.858

0.103

0.633

-1.181

0.156

-1.016

0.113

0.494

0.549

3.005

0.037

-8.018

0.123

B. In the adult group

Age

0.061

0.006

0.097

0.004

0.011

0.380

0.008

0.488

0.008

0.821

-0.032

0.240

0.074

0.067

0.067

0.038

0.167

0.014

Sex

-0.027

0.965

2.498

0.009

-0.204

0.574

-0.076

0.805

-0.569

0.565

-0.362

0.639

0.124

0.910

0.103

0.910

-4.965

0.591

BSA

5.347

0.001

14.027

<0.001

1.615

0.065

1.569

0.036

7.383

0.002

4.600

0.015

-0.631

0.811

-0.102

0.962

102.379

<0.001

OI

-0.205

0.730

-3.621

<0.001

-0.365

0.298

-0.280

0.352

-0.883

0.355

-0.629

0.398

0.532

0.620

0.147

0.866

58.928

<0.001

  1. Abbreviations OI: osteogenesis imperfecta; BSA: body surface area; SBP: systolic blood pressure; DBP: diastolic blood pressure; AD: aorta diameter; LAD: left atrium diameter; IVST: interventricular septum thickness; LVPWT: left ventricular posterior wall thickness; LVEDd: left ventricular end-diastolic diameter; LVESd: left ventricular end-systolic diameter; LVEF: left ventricular ejection fraction; FS: fractional shortening; LVM: Left ventricular mass. Bold P values indicate significance.