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Table 1 Comparison of phenotype according to etiology of obesity

From: Hyperphagia and impulsivity: use of self-administered Dykens’ and in-house impulsivity questionnaires to characterize eating behaviors in children with severe and early-onset obesity

 

HO (n = 15)

mean ± SD

[min–max]

ID (n = 19)

mean ± SD

[min–max]

CO (n = 41)

mean ± SD

[min–max]

P value

Age, years (n = 75)

8.1 ± 4.7

10.9 ± 3.9

11.7 ± 4.1

0.04

Sex ratio, M/F (n = 75)

7/8

8/11

21/20

0.80

BMI Z-score, DS (n = 75)

5.1 ± 2.6

4.6 ± 1.2

5.0 ± 1.1

0.39

Age when BMI crosses IOTF30, years (n = 64)

2.3 ± 2.0 [0.9–3.0]

3.8 ± 2.0 [2.6–5.0]

4.3 ± 3.1 [2.0–5.7]

0.04

Age when BMI crosses IOTF40, years (n = 31)

3.4 ± 1.6 [3.0–6.0]

4.6 ± 1.6 [4.0–6.0]

8.4 ± 4.1 [6.0–13.0]

 < 0.01

Age at adiposity rebound, year (n = 31)

1.7 ± 1.8 [1.1–2.4]

1.9 ± 0.8 [1.5–2.0]

2.6 ± 1.4 [2.0–4.0]

0.53

Children with BMI > IOTF30 at 3 years (%) (n = 34)

10 (67)

9 (53)

14 (44)

0.34

Children with BMI > IOTF30 at 6 years (%) (n = 53)

11 (79)

16 (94)

26 (79)

0.38

Absence of adiposity rebound (%) (n = 37)

13/15 (87)

12/19 (63)

12/36 (33)

 < 0.01

Dykens’, total

24.9 ± 9.2 [17–32]

23.0 ± 8.5 [20–30]

20.7 ± 5.3 [17–23]

0.11

Dykens’, hyperphagic behavior

10.6 ± 5.4

9.9 ± 4.9

8.8 ± 2.5

0.71

Dykens’, drive

10.4 ± 3.5

9.3 ± 3.1

8.9 ± 3.3

0.32

Dykens’, severity

4.2 ± 2.4

3.8 ± 2.2

3.0 ± 1.2

0.07

Dykens’, total > 19 (%)

10/15 (67)

14/19 (74)

26/41 (63)

0.63

Impulsivity > 7 (%)

2/15 (13)

1/15 (7)

8/41 (20)

ND

  1. BMI, body mass index; CO, common obesity with early-onset; HO, hypothalamic obesity; ID, intellectual deficiency with obesity; IOTF, International Obesity Task Force; NS, not significant; SD, standard deviation; ND, not determined
  2. Bold values indicate P < 0.05