Table 3 Skindex-29 results in NF1 patients stratified by sex, age group, education level, disease visibility (Ablond’s score) and disease severity (Riccardi’s score)

Sex

Females

40

21

52.5

19.0 (9.3–23.6)

25.0 (7.5–42.5)

10.7 (0.0-19.7)

12.5 (2.1–19.8)

Males

40

19

47.5

7.1 (4.0-18.6)

7.5 (5.0–20.0)

7.1 (0.0-17.9)

2.1 (0.0-12.5)

p value^a

0.034

0.061

0.688

0.088

Age (years)

< 35

40

17

42.5

10.3 (6.0-21.3)

20.0 (5.0–35.0)

7.1 (0.0-14.3)

4.2 (0.0-18.7)

35–54

40

14

35.0

19.1 (6.0-25.9)

11.3 (5.0-51.3)

16.1 (0.0-36.6)

6.3 (0.0-20.4)

>=55

40

9

22.5

12.3 (4.2–21.9)

17.5 (6.3–37.5)

7.1 (0.0-14.3)

10.4 (2.0-15.7)

p value^a

0.759

0.999

0.209

0.920

Ablond’s score

Grade 1

40

12

30.0

9.7 (5.3–20.7)

10.0 (5.0-36.3)

1.8 (0.0-13.4)

2.1 (0.0-15.6)

Grade 2

40

17

42.5

13.6 (6.6–24.0)

17.5 (6.3–37.5)

7.1 (1.8–23.2)

12.5 (1.1–16.7)

Grade 3

40

11

27.5

10.3 (2.6–30.6)

10.0 (5.0–50.0)

14.3 (0.0-21.4)

10.4 (2.0–25.0)

p value^b

0.545

0.825

0.207

0.397

Riccardi’s score

Grade 1

40

5

12.5

6.4 (5.8–9.7)

5.0 (5.0–15.0)

10.7 (3.6–14.3)

2.1 (0.0-9.4)

Grade 2

40

16

40.0

11.0 (4.3–22.4)

15.0 (5.0–25.0)

3.6 (0.0-23.2)

3.2 (0.0-14.1)

Grade 3

40

15

37.5

18.6 (8.8–33.8)

25.0 (7.5–50.0)

14.3 (0.0-21.4)

12.5 (2.1–25.0)

Grade 4

40

4

10.0

13.4 (3.3–27.7)

21.3 (5.0-48.8)

10.7 (1.8–14.3)

8.4 (1.1.21.9)

p value^b

0.202

0.173

0.876

0.130