Table 2 Enzymatic deficiencies associated with hemolytic anemia

Most common

G6PD deficiency

AR

PK deficiency

AR

Impaired mental development

Phosphoglycerate kinase deficiency

X-linked

Glutathione synthetase deficiency

AR

Triosephosphate isomerase deficiency

AR

Myopathy

Phosphofructokinase deficiency

AR

Phosphoglycerate kinase deficiency

X-linked

Less common without extra-hematological symptoms

P5′N (most common after G6PD and PK deficiency)

AR

Adenylate kinase deficiency

AR

GPI deficiency

AR

Hexokinase deficiency

AR

Glutathione reductase deficiency*

AR