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Fig. 5 | Orphanet Journal of Rare Diseases

Fig. 5

From: Transcriptional profiling of peripheral blood mononuclear cells identifies inflammatory phenotypes in Ataxia Telangiectasia

Fig. 5

Identification and characterization of protein biomarkers of A-T disease severity. A) Matrixplot of expression of differentially expressed genes across classic A-T and unaffected individuals, restricted to those genes whose protein products are detectable by blood plasma immunoassay or mass-spectrometry according to the Human Protein Atlas. B,D,E) Boxplots of protein concentrations in blood plasma by ELISA for PAI-1 (SERPINE1) (B), VEGFR3 (FLT4) (D), and GP130 (IL6ST) (E), stratified by condition. C) Linear regression of PAI-1 plasma concentration versus age in individuals with classic A-T

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172