Table 2 Demographic and clinical characteristics according to age
From: RegistrAME: the Spanish self-reported patient registry of spinal muscular atrophy
Variable | AGE: Years | |||||
|---|---|---|---|---|---|---|
< 2 | 2–6 | 7–10 | 11–15 | > 15 | ||
N = 11 | N = 67 | N = 37 | N = 32 | N = 148 | ||
Sex | Female | 8 (72.73%) | 33 (49.25%) | 16 (43.24%) | 11 (34.38%) | 68 (45.95%) |
Male | 3 (27.27%) | 34 (50.75%) | 21 (56.76%) | 21 (65.62%) | 80 (54.05%) | |
Functional Status | Non-sitter | 9 (81.82%) | 6 (8.96%) | 8 (21.62%) | 10 (31.25%) | 52 (35.14%) |
Sitter | 2 (18.18%) | 43 (64.18%) | 23 (62.16%) | 18 (56.25%) | 63 (42.57%) | |
Walker | 0 (0%) | 18 (26.87%) | 6 (16.22%) | 4 (12.5%) | 33 (22.3%) | |
SMA type | 1 | 11 (100%) | 36 (53.73%) | 10 (27.03%) | 3 (9.38%) | 5 (3.38%) |
2 | 0 (0%) | 25 (37.31%) | 22 (59.46%) | 24 (75%) | 72 (48.65%) | |
3 | 0 (0%) | 6 (8.96%) | 5 (13.51%) | 5 (15.62%) | 69 (46.62%) | |
4 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 2 (1.35%) | |
SMN 2 copy number* | 2 | 11 (100%) | 36 (53.73%) | 10 (29.41%) | 2 (7.69%) | 8 (6.4%) |
3 | 0 (0%) | 31 (46.27%) | 23 (67.65%) | 19 (73.08%) | 93 (74.4%) | |
4 | 0 (0%) | 0 (0%) | 1 (2.94%) | 5 (19.23%) | 24 (19.2%) | |
Scoliosis Surgery | No | 11 (100%) | 66 (98.51%) | 32 (86.49%) | 14 (43.75%) | 70 (47.3%) |
Yes | 0 (0%) | 1 (1.49%) | 5 (13.51%) | 18 (56.25%) | 78 (52.7%) | |
Gastrostomy | No | 11 (100%) | 51 (76.12%) | 30 (81.08%) | 32 (100%) | 142 (95.95%) |
Yes | 0 (0%) | 16 (23.88%) | 7 (18.92%) | 0 (0%) | 6 (4.05%) | |
SMN Treatment | No | 0 (0%) | 0 (0%) | 1 (2.7%) | 3 (9.38%) | 65 (43.92%) |
Yes | 11 (100%) | 67 (100%) | 36 (97.3%) | 29 (90.62%) | 83 (56.08%) | |