Skip to main content

Table 3 Healthcare Costs for Patients with VHL-CNS-Hb or VHL-pNET

From: Epidemiology and economic burden of Von Hippel-Lindau Disease-associated central nervous system hemangioblastomas and pancreatic neuroendocrine tumors in the United States

 

Tumor-Related Healthcare Costs3

All-Cause Predicted Costs

All-Cause Cost Difference

Annual Healthcare Costs (2020 USD)

Cases

Cases

Controls

Unadjusted Model

 

Adjusted Model

 

VHL-CNS-Hb (220 cases, 1,100 controls)

       

Total costs1

-

$70,924

$11,418

$59,505

***

$49,645

***

Medical costs

$22,379

$61,919

$9,094

$52,825

***

$45,090

***

Inpatient costs

$19,145

$39,548

$3,915

$35,633

***

$36,430

***

Outpatient costs

$2,437

$16,750

$4,210

$12,540

***

$9,115

***

ED costs

$300

$3,657

$730

$2,927

***

$2,309

***

Other costs2

$497

$1,963

$239

$1,724

***

$1,689

***

Pharmacy costs1

-

$9,005

$2,325

$6,681

***

$4,206

***

VHL-pNET (20 cases, 100 controls)

       

Total costs1

-

$97,661

$8,782

$88,879

***

$56,580

*

Medical costs

$22,325

$81,359

$5,906

$75,453

***

$46,538

*

Inpatient costs

$16,003

$50,087

$1,258

$48,829

***

$34,585

*

Outpatient costs

$6,286

$28,298

$3,951

$24,347

***

$16,731

*

ED costs

$30

$2,357

$583

$1,773

**

$2,026

**

Other costs2

$6

$617

$114

$503

**

$879

**

Pharmacy costs

-

$16,302

$2,876

$13,426

**

$8,703

*

  1. Abbreviations: CNS: central nervous system; ED: emergency department; Hb: hemangioblastoma; pNET: pancreatic neuroendocrine tumor; VHL: von Hippel-Lindau; USD: United States dollars
  2. Notes:
  3. * denotes P-values < 0.05; ** denotes P-values < 0.01; *** denotes P-values < 0.001
  4. 1. Because pharmacy claims do not have corresponding diagnosis codes, the tumor-related total costs and pharmacy costs could not be calculated
  5. 2. “Other” medical costs include all those not captured by inpatient, ED, or outpatient costs. These claims may reflect home health aids or physician visits among other types of ancillary medical claims
  6. 3. A claim was defined as “tumor-related” if it also had a corresponding diagnosis associated with it. See Jonasch et al. for the list of codes used for each tumor type [7]