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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Epidemiology and economic burden of Von Hippel-Lindau Disease-associated central nervous system hemangioblastomas and pancreatic neuroendocrine tumors in the United States

Fig. 2

Rates and Costs Associated with CNS-Hb Tumor Reduction Procedure Complications1,2,3. Abbreviations: CNS: central nervous system; Hb: hemangioblastoma; PNET: pancreatic neuroendocrine tumor; TRP: tumor reduction procedure; USD: United States dollar; VHL: von Hippel-Lindau. Notes: * denotes P-values < 0.05; ** denotes P-values < 0.01. (1) In total, 39 tumor reduction procedures were considered in this analysis. Proportions are calculated with the total number of tumor reduction procedures as the denominator. (2) Complications associated with CNS-Hb reduction procedures were classified as any associated diagnoses or procedures related to a medical complication following a CNS-Hb reduction procedure. (3) Costs of tumor reduction procedure complications were estimated via univariate generalized linear models, using a Tweedie distribution and log link function. These models compared costs between patients who had a complication versus those who did not

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172