Fig. 5

Comparison between the efficacy of the test drug in single-arm trials and that of the virtual placebo group under the same conditions. Note: a Overall Survival of Lithium carbonate; b ALSFRS-R of VM202; The black dashed line epresents the typical value of the placebo group at the same baseline predicted by the model, the shading represents its 95% CI, and the dots represent the measured efficacy in the single-arm trial; m, month