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Table 1 Mean, standard deviation, skewness, kurtosis, Shapiro–Wilk, McDonald ω, Cronbach's α, Spearmen Correlation analysis, and Confirmatory Factor Analysis of MECP2 Duplication Syndrome Specific Gastrointestinal Health Scale

From: Development and validation of parent-reported gastrointestinal health scale in MECP2 duplication syndrome

Items

Mean

Standard deviation

Skewness

Kurtosis

Shapiro Wilk

McDonald ω (If item deleted)

Cronbach's α (If item deleted)

Spearman correlation coefficient

p-value for Spearman

CFA gactor loadings

95% CI

p-value

Lower

Upper

General HealthQ1

1.500

1.148

.423

-.453

 < .001

0.921

0.925

0.665

 < .001

0.923

0.877

0.970

 < .001

General HealthQ2

1.425

1.179

.220

-.952

 < .001

0.921

0.925

0.648

 < .001

0.907

0.861

0.953

 < .001

GeneralHealthQ3

1.160

1.212

.830

-.288

 < .001

0.923

0.926

0.532

 < .001

0.660

0.604

0.717

 < .001

ECSQ1

1.292

1.493

.815

-.772

 < .001

0.924

0.926

0.520

 < .001

0.785

0.725

0.845

 < .001

ECSQ2

2.443

1.421

-.299

-1.271

 < .001

0.924

0.926

0.536

 < .001

0.736

0.677

0.795

 < .001

ECSQ3

2.038

1.603

-.020

-1.559

 < .001

0.923

0.926

0.605

 < .001

0.780

0.718

0.843

 < .001

ECSQ4

2.594

1.419

-.551

-1.017

 < .001

0.927

0.929

0.293

0.002

0.375

0.306

0.444

 < .001

ECSQ5

1.943

1.440

.179

-1.261

 < .001

0.923

0.925

0.607

 < .001

0.842

0.786

0.899

 < .001

ECSQ6

1.698

1.318

.297

-.934

 < .001

0.923

0.926

0.542

 < .001

0.800

0.744

0.857

 < .001

ECSQ7

1.274

1.760

.791

-1.256

 < .001

0.925

0.927

0.524

 < .001

0.804

0.742

0.867

 < .001

ECSQ8

2.085

1.651

-.112

-1.616

 < .001

0.928

0.930

0.290

0.003

0.340

0.272

0.407

 < .001

RefluxQ1

1.509

1.361

.326

-1.138

 < .001

0.923

0.926

0.526

 < .001

0.847

0.787

0.908

 < .001

RefluxQ2

0.906

1.109

1.344

1.333

 < .001

0.923

0.926

0.455

 < .001

0.842

0.782

0.902

 < .001

RefluxQ3

1.283

1.225

.739

-.223

 < .001

0.921

0.925

0.613

 < .001

0.929

0.855

1.003

 < .001

MotilityQ1

2.736

1.174

-.766

-.002

 < .001

0.923

0.926

0.556

 < .001

0.943

0.869

1.017

 < .001

MotilityQ2

2.113

1.174

-.044

-.632

 < .001

0.925

0.927

0.379

 < .001

0.654

0.592

0.717

 < .001

MotilityQ3

2.406

1.067

-.396

-.097

 < .001

0.924

0.927

0.439

 < .001

0.660

0.593

0.728

 < .001

MotilityQ4

2.849

1.440

-.843

-.726

 < .001

0.924

0.927

0.420

 < .001

0.675

0.597

0.752

 < .001

MoodQ1

1.226

1.098

.593

-.286

 < .001

0.923

0.926

0.517

 < .001

0.824

0.776

0.873

 < .001

MoodQ2

1.236

1.038

.708

.180

 < .001

0.922

0.925

0.629

 < .001

0.926

0.881

0.972

 < .001

MoodQ3

1.179

1.128

.734

-.264

 < .001

0.923

0.926

0.556

 < .001

0.863

0.819

0.906

 < .001

MoodQ4

1.208

1.084

.626

-.171

 < .001

0.923

0.926

0.464

 < .001

0.838

0.792

0.884

 < .001

MoodQ5

1.575

1.086

.416

-.199

 < .001

0.923

0.926

0.518

 < .001

0.860

0.815

0.906

 < .001

MedicationQ1

0.670

1.144

1.769

2.199

 < .001

0.925

0.927

0.466

 < .001

0.650

0.564

0.735

 < .001

MedicationQ2

1.189

1.768

.909

-1.115

 < .001

0.925

0.927

0.524

 < .001

0.858

0.762

0.954

 < .001

MedicationQ3

0.755

1.459

1.656

.987

 < .001

0.927

0.929

0.274

0.004

0.512

0.422

0.603

 < .001

MedicationQ4

0.142

0.608

5.351

30.600

 < .001

0.925

0.928

0.246

0.011

0.746

0.641

0.852

 < .001

MedicationQ5

0.245

0.803

3.694

13.548

 < .001

0.925

0.928

0.215

0.027

0.661

0.569

0.754

 < .001

MedicationQ6

1.406

1.689

.583

-1.431

 < .001

0.927

0.930

0.320

 < .001

0.454*

0.371

0.537

 < .001

MedicationQ7

2.302

1.730

-.288

-1.669

 < .001

0.928

0.930

0.314

0.001

0.402*

0.320

0.484

 < .001

ParentingQ1

2.038

1.129

.087

-.339

 < .001

0.923

0.924

0.718

 < .001

0.890

0.855

0.885

 < .001

ParentingQ2

2.689

1.190

-.685

-.336

 < .001

0.923

0.925

0.568

 < .001

0.849

0.813

0.957

 < .001

ParentingQ3

1.849

1.293

.179

-.974

 < .001

0.923

0.924

0.709

 < .001

0.926

0.895

0.833

 < .001

ParentingQ4

2.726

1.276

-.646

-.633

 < .001

0.923

0.925

0.592

 < .001

0.791

0.750

0.925

 < .001

ParentingQ5

1.858

1.558

.163

-1.509

 < .001

0.923

0.925

0.639

 < .001

0.893

0.861

0.953

 < .001

ParentingQ6

1.575

1.387

.540

-.832

 < .001

0.923

0.924

0.694

 < .001

0.921

0.890

0.922

 < .001

ParentingQ7

1.811

1.468

.242

-1.287

 < .001

0.922

0.924

0.730

 < .001

0.888

0.854

0.928

 < .001

ParentingQ8

2.472

1.402

-.448

-.997

 < .001

0.923

0.925

0.653

 < .001

0.893

0.859

0.925

 < .001

  1. CFA: Confirmatory Factor Analysis; CI: Confidence Interval; ECS: Eating-Chewing-Swallowing; Q: Question
  2. *Factor loadings below 0.5 are bolded
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172