Table 1 Inclusion and exclusion criteria

Population

Patients older than 12 months at the time of diagnosis

Patients younger than 12 months at the time of diagnosis

Design

Any study design that includes clinical data of patients with late onset CblC disease

Any study design that does not include clinical data of patients with late onset CblC disease

Intervention

Clinical spectrum of the late onset cblC desease

Comparator

Not applicable

Outcome

Types of clinical presentation, modes of diagnosis, biochemical and clinical response to treatment, general outcome

Country

All countries

Method

Primary studies

Narrative reviews

Expert opinions

Editorials

Qualitative studies

Publication type

Published in peer-reviewed databases

Conference papers

Dissertations

Books/books chapters

Unpublished material

Grey literature

Year of publications

Published in any year

Language

English and Spanish

Other languages

Other

Humans

Animal studies