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Table 3 Cronbach’s alpha (α), retest reliability, and Pearson correlations with EQ-5D-5L, FARS-ADL, and the caregiver questionnaire

From: Development and validation of TreatHSP-QoL: a patient-reported outcome measure for health-related quality of life in hereditary spastic paraplegia

 

Items

Cronbach’s

α

Retest

[95% CI]

EQ-5D-5L

[95% CI]

FARS-ADL

[95% CI]

Caregivers

[95% CI]

General QoL and attitude to disease

6

0.85

0.86

[0.79, 0.91]

0.37

[0.25, 0.48]

−0.18

[−0.30, −0.06]

0.64

[0.36, 0.81]

Mobility and leisure time

6

0.80

0.83

[0.74, 0.89]

0.52

[0.42, 0.61]

−0.59

[−0.67, −0.50]

0.75

[0.53, 0.87]

Medical care

4

0.80

0.78

[0.67, 0.85]

0.12

[−0.01, 0.25]

−0.05

[−0.17, 0.08]

0.72

[0.47, 0.85]

Social life and occupation/work

5

0.60

0.83

[0.74, 0.89]

0.30

[0.17, 0.41]

−0.22

[−0.34, −0.09]

0.71

[0.47, 0.85]

Associated symptoms

4

0.57

0.86

[0.78, 0.90]

0.34

[0.22, 0.45]

−0.45

[−0.55, −0.34]

0.82

[0.65, 0.91]

Total score

25

0.85

0.86

[0.79, 0.91]

0.53

[0.42, 0.61]

−0.46

[−0.55, −0.35]

0.65

[0.38, 0.81]

  1. EQ-5D-5L, EuroQol-5 Dimension (5 levels); FARS-ADL, Friedreich Ataxia Rating Scale-Activities of Daily Living; QoL, quality of life