Fig. 3From: Development and validation of TreatHSP-QoL: a patient-reported outcome measure for health-related quality of life in hereditary spastic paraplegiaOverview of the TreatHSP-QoL development process. Three step approach with (I) pilot item generation relying on qualitative data analysis from the interviews, (II) pilot item validation on a small sample of patients and caregivers and (III) main validation on a larger sample of patients and caregivers. The figure also includes the aspects of development and modification shown in results sectionBack to article page