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Table 3 Excipients not recommended for HFI patients

From: Design of mobile and website health application devices for drug tolerability in hereditary fructose intolerance

Not recommended excipients

Comments

Mannitol (E 421) (intravenous)

Fructose polyalcohol. Oral mannitol has an absorbance of 25–65%. In the liver, 7–10% of absorbed mannitol can be transformed into fructose or oxidised to CO2 by unknown pathways [5, 23, 24].

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172