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Table 1 Proteomics analysis of vEDS and wild type fibroblasts

From: Dysregulation of extracellular matrix and Lysyl Oxidase in Ehlers-Danlos syndrome type IV skin fibroblasts

Proteins Increased in vEDS

Proteins Decreased in vEDS

Protein Symbol

Log2 Fold Change

P-Value

Protein Symbol

Log2 Fold Change

P-Value

COL8A1

3.59

0.00725

ADAMTSL4

4.99

0.01604

LOXL2

2.99

0.00771

SPON2

3.98

0.00132

COL12A1

2.91

0.00319

CLU

3.1

0.00012

COL2A1

2.82

0.00554

THSD4

2.62

0.00061

POSTN

2.79

0.00050

VTN

2.61

0.01925

COL5A2

2.72

0.00972

SERPINE2

2.49

0.01213

BGN

2.57

0.02018

TNXB

2.32

0.01365

FLRT2

2.09

0.01790

TGFBR3

2.2

0.00686

COL3A1

2.02

0.00004

DCN

2.13

0.00438

COL5A1

1.99

0.00349

TIMP1

1.92

0.01442

  1. *See Supplemental Data for additional proteomics data analysis