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Table 6 Comparison of patients with the lowest and highest baseline triglyceride levels at baseline

From: Impact of lipodystrophy on health-related quality of life: the QuaLip study

 

Lowest triglyceride tertile

(n = 22)

Highest triglyceride tertile

(n = 22)

p value

Age

39 (29–52)

35 (26–44)

0.250

Height (cm)

165 (162–173)

160 (155–165)

0.109

Weight (kg)

67 (57–75)

53 (50–62)

0.009

BMI (kg/m2)

24.20 (20.76–28.24)

20.70 (18.37–25.08)

0.033

HbA1c (%)

6.0 (5.6–8.0)

7.3 (6.4–9.3)

0.015

FBG (mg/dL)

95.50 (89.00–145.00)

150.00 (111.00–190.00)

0.022

Triglyceride (mg/dL)

128.50 (100.00–144.00)

608.50 (485.00–888.00)

 < 0.001

LDL (mg/dL)

123.50 (95.00–137.00)

113.50 (91.00–125.00)

0.359

HDL (mg/dL)

43.50 (35.00–51.00)

29.50 (25.00–33.50)

0.001

Leptin (ng/mL)

7.06 (2.91–12.77)

0.97 (0.38–4.19)

0.015

ALT (U/L)

23.50 (18–28.50.00)

23.00 (15.00–29.00)

0.876

WBC (103/μL)

7.50 (6.70–8.90)

7.40 (6.80–8.60)

0.900

Hemoglobin (g/dL)

13.00 (12.70–13.80)

12.40 (11.60–13.40)

0.249

Hematocrit (%)

40.00 (37.80–40.70)

36.60 (34.80–39.50)

0.079

Platelet (103/μL)

257.50 (180.50–327.50)

281.00 (221.00–356.00)

0.214

SF36_PF

80.00 (45.00–90.00)

60.00 (45.00–85.00)

0.532

SF36_RP

75.00 (25.00–100.00)

0.00 (0.00–100.00)

0.036

SF36_RE

66.67 (33.33–100.00)

0.17 (0.00–66.67)

0.056

SF36_VT

55.00 (50.00–75.00)

40.00 (20.00–65.00)

0.073

SF36_MH

62.00 (52.00–76.00)

52.00 (40.00–64.00)

0.157

SF36_SF

75.00 (62.50–100.00)

62.50 (37.50–75.00)

0.058

SF36_BP

78.75 (45.00–100.00)

50.00 (32.50–90.00)

0.071

SF36_GH

45.00 (30.00–60.00)

30.00 (30.00–45.00)

0.121

Beck depression score

12.50 (5.00–22.00)

18.00 (7.00–25.00)

0.176

EQ-5D-5L index value

0.71 (0.64–0.88)

0.50 (0.16–0.76)

0.041

EQ-5D-5L VAS

80.00 (75.00–90.00)

67.50 (50.00–80.00)

0.052

Facit fatigue score

32.50 (24.00–42.00)

23.00 (15.00–35.00)

0.069

  1. Data presented as median (25–75 percentiles). Categorical data are shown as n (%). P values are calculated using the Mann–Whitney U test for continuous variables and the chi-square test for categorical parameters
  2. BMI, Body Mass Index; HbA1c, Hemoglobin A1c; FBG, Fasting Blood Glucose; LDL, Low-Density Lipoprotein; HDL, High-Density Lipoprotein; ALT, Alanine Transaminase; WBC, White Blood Cell Count; SF36_PF, Physical Functioning; SF36_RP, Role Limitations due to Physical Health; SF36_BP, Pain; SF36_GH, General Health SF36_VT, Vitality; SF36_SF, Social Functioning; SF36_RE, Role Limitations due to Emotional Problems; SF36_MH, Mental Health; VAS, Visual Analog Scale
  3. All subjects were leptin naïve at baseline. Facit Fatigue total score ranges from 0 to 52. Lower scores indicate greater fatigue