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Table 5 Comparison of QoL measures in patients with and without a psychiatric diagnosis at the baseline visit

From: Impact of lipodystrophy on health-related quality of life: the QuaLip study

 

Diagnosed with a psychiatric disease

(n = 18)

No psychiatric diagnosis at the baseline visit

(n = 47)

p value

Age

34 (28–42)

37 (27–51)

0.304

Gender

0.817

Female

15 (83.33%)

38 (80.85%)

Male

3 (16.67%)

9 (19.15%)

Type of lipodystrophy

0.099

CGL

7 (38.89%)

9 (19.15%)

FPLD

11 (61.11%)

29 (61.70%)

APL

0 (0.00%)

9 (19.15%)

SF36_PF

50.00 (20.00–85.00)

80.00 (45.00–90.00)

0.033

SF36_RP

12.50 (00.00–50.00)

75.00 (00.00–100.00)

0.015

SF36_RE

00.00 (00.00–33.33)

66.67 (00.00–100.00)

0.005

SF36_VT

30.00 (20.00–55.00)

55.00 (35.00–80.00)

0.002

SF36_MH

40.00 (24.00–56.00)

60.00 (48.00–76.00)

0.003

SF36_SF

43.75 (25.00–62.50)

75.00 (62.50–87.50)

0.001

SF36_BP

45.00 (32.50–57.50)

67.50 (45.00–100.00)

0.014

SF36_GH

20.00 (10.00–30.00)

45.00 (30.00–60.00)

 < 0.001

Beck Depression Score

21.50 (14.00–33.00)

14.00 (6.00–22.00)

0.009

EQ-5D-5L index value

0.39 (0.17–0.68)

0.72 (0.33–0.88)

0.008

EQ-5D-5L VAS

50.00 (40.00–75.00)

80.00 (60.00–90.00)

0.004

Facit Fatigue Score

20.50 (16.00–28.00)

29.00 (22.00–43.00)

0.012

  1. Clinical psychiatric evaluation was not completed in 2 (FPLD) patients. Data presented as median (25–75 percentiles). Categorical data shown as n (%). P values are calculated using Mann–Whitney U test for continuous variables and chi square test for categorical parameters
  2. Abbreviations used in the table; CGL, Congenital Generalized Lipodystrophy; FPLD, Familial Partial Lipodystrophy; BMI, Body Mass Index; HbA1c, Hemoglobin A1c; FBG, Fasting Blood Glucose; LDL, Low Density Lipoprotein; HDL, High Density Lipoprotein; ALT, Alanine Transaminase; WBC, White Blood Cell Count; SF36_PF, Physical Functioning; SF36_RP, Role Limitations due to Physical Health; SF36_BP, Pain; SF36_GH, General Health SF36_VT, Vitality; SF36_SF, Social Functioning; SF36_RE, Role Limitations due to Emotional Problems; SF36_MH, Mental Health; VAS, Visual Analog Scale. Facit Fatigue total score ranges from 0 to 52. Lower scores indicate greater fatigue