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Table 2 Proportion of patients with EQ-5D-5L VAS score < 60, and Beck Depression Inventory (BDI) and Facit Fatigues scores at each visit

From: Impact of lipodystrophy on health-related quality of life: the QuaLip study

 

Baseline (V1)

(n = 67)

Month 3 (V2)

(n = 60)

Month 6 (V3)

(n = 64)

Month 9 (V4)

(n = 64)

Year-1 (V5)

(n = 60)

Month 15 (V6)

(n = 58)

Month 18 (V7)

(n = 59)

Month 21 (V8)

(n = 57)

Year-2 (V9)

(n = 56)

EQ-5D 5L

VAS score < 60, n

20

26

26

25

28

27

26

24

21

VAS score < 60, %

29.85

43.33

40.63

39.06

46.67

46.55

44.07

42.11

37.50

BDI

Median

16.00

17.50

16.50

13.50

12.50

15.50

13.00

17.00

12.50

25 percentiles

7.00

9.00

8.00

06.00

6.00

6.75

5.00

5.00

5.00

75 percentiles

24.00

26.75

26.00

29.25

26.75

29.00

26.00

27.50

25.75

Facit Fatigues score

Median

27.00

25.00

26.50

30.50

32.50

31.50

33.00

33.00

28.00

25 percentiles

17.00

17.25

15.00

16.25

18.00

14.75

17.00

18.50

17.00

75 percentiles

38.00

39.00

40.75

41.00

40.75

41.25

40.00

44.00

45.00

  1. Data presented as median (25–75 percentiles)
  2. BDI, Beck Depression Inventory; VAS, Visual Analogue Scale
  3. Facit Fatigue total score ranges from 0 to 52. Lower scores indicate greater fatigue. Per local regulations, no data was collected on leptin replacement status during follow-up. All subjects were leptin naïve at baseline; however, it is likely that a subset of subjects with GL received leptin replacement during follow-up that may have caused elevations in leptin levels at year-2 visit