Fig. 5

Percent predicted diffusing  capacity of the lung for carbon monoxide (DL_CO) adjusted for hemoglobin and barometric pressure during placebo or olipudase alfa treatment periods. Means are shown above and below the lines for the group crossing over to olipudase alfa from placebo and the olipudase alfa group, respectively. Percent predicted DL_CO values > 80% were considered normal without impairment, > 60–80% mild impairment, 40–60% moderate impairment, and < 40% severe impairment [29, 30]