Table 3 Win ratio analysis comparing pairs of patients on clinically meaningful improvement or decline in the two measures in the order indicated
Measure | Order of comparison of endpoints | |
|---|---|---|
FVC % Predicted 6MWT | 6MWT FVC % Predicted | |
Comparison based on the first endpoint in the sequence | ||
Wins | 923 | 786 |
Losses | 417 | 330 |
Ties | 1159 | 1383 |
Comparison based on second endpoint in the sequence | ||
Wins | 314 | 391 |
Losses | 106 | 253 |
Ties | 739 | 739 |
Totals | ||
Wins | 1237 | 1177 |
Losses | 523 | 583 |
Ties | 739 | 739 |
Win ratio (95% CI) | 2.37 (1.30, 4.29) | 2.02 (1.13, 3.62) |
p-value | 0.005 | 0.018 |