Table 2 Stratification and radiological severe lung lesions effect on survival
Event | N | % | OS (%) | P | CI | EFS (%) | P | CI (%) |
|---|---|---|---|---|---|---|---|---|
LCH total | 350 | |||||||
Severe lung | 24 | 7 | 73.3 | 0.001 | 57.4–94.3% | 43 | 0.011 | 26.6–69.6 |
No severe lung | 43 | 13 | 95 | 88.4–100% | 64.8 | 50.8–82.7 | ||
No lung involvement | 283 | 81 | 93.6 | 90.4–96.4% | 62.5 | 56.8–68.7 | ||
RO− | 279 | |||||||
With severe lung | 13 | 4 | 100 | 0.83 | NA | 47 | 0.04 | 16.6–77.4 |
With no severe lung | 266 | 76 | 99.6 | 99.8–100% | 69 | 63.1–74.9 | ||
RO+ | 71 | |||||||
With severe lung | 11 | 15 | 45.5 | 0.12 | 16.1–74.9% | 36.4 | 0.44 | 8–64.8 |
With no severe lung | 60 | 85 | 67 | 54.9–79.2% | 35.8 | 23.3–48.3 | ||
Liver | 127 | |||||||
Severe lung | 11/24 | 46 | 46 | < 0.001 | 23.8–86.8% | 27.3 | 0.003 | 10.4–71.6 |
No Severe lung | 116/326 | 36 | 85.2 | 78.8–92.2% | 49.8 | 41.1–60.4 | ||
Splenomegaly | 43 | |||||||
Severe lung | 5/24 | 21 | 20 | 0.009 | 3.5–100% | 20 | 0.2 | 3.5–100 |
No severe lung | 38/326 | 12 | 61.8 | 48–79.8% | 31 | 18.7–50.8 | ||
Hemopoietic system | 42 | |||||||
Severe lung | 8/24 | 33 | 43.8 | 0.09 | 18.9–100% | 43.8 | 0.8 | 18.9–100 |
No severe lung | 34/326 | 10 | 70.1 | 56.1–87.5% | 29.1 | 17.2–49.4 |