Table 4 Patient´s characteristics in relation to genotype and developmental outcome, n = 21 (age, mean ± SD: 7.4 ± 6.9 years)
Cognitive ability | Average | Below average (< 2SD) | Subgroup: Severe cognitive impairment |
|---|---|---|---|
n (%) | n (%) | n (%) | |
Genotype | |||
 TSC1 | 2/6 (33.3) | 4/6 (66.7) | 2/6 (33.3) |
 TSC2 | 5/15 (33.3) | 10/15 (66.7) | 4/15 (26.7) |
Epilepsy | |||
 Age at manifestation (years), mean ± SD | 3.45 ± 4.12 | 0.48 ± 0.56 | 0.19 ± 0.19* |
 No epilepsy, N | 2 | 2 | - |
 Epilepsy with focal seizures, N (%) | 4/11 (36.3) | 7/11 (63.7) | 2/11 (18.2) |
 Multifocal epilepsy with various seizures types (incl. West syndrome, LGS), N (%) | 1/6 (16.7) | 5/6 (83.3) | 4/6 (66.7) |
Seizure freedom (last visit) | |||
 No seizure freedom (last visit) | 4/12 (33.3) | 8/12 (66.7) | 3/12 (25.0) |
 Seizure freedom > 1 year (last visit) | 1/5 (20.0) | 4/5 (80.0) | 3/5 (60.0) |