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Table 1 Overall features of the 14 patients with chronic intestinal (IBD-like) inflammation (either EE or CD-like). A positive HAEC status means that the patient experienced previous episodes of enterocolitis. All but one patients (ID 1) had pathological evidence of acute inflammation or infiltrate

From: A unicentric cross-sectional observational study on chronic intestinal inflammation in total colonic aganglionosis: beware of an underestimated condition

ID

Sex

Age [years]

Type of P-T

Pathology

Comorbidities

RET mut

Years from P-T

FC [µg/g]

OFB

SEMA-CD

PCDAI

HAEC status

1

F

1,5

ERPT

EE

None

No

0.6

16

Positive

0

5

Positive

2

F

2,4

ERPT

EE

None

Yes

1.4

1398

Negative

0

10

Negative

3

F

4.2

ERPT

CD-Like

None

N.A.

3.4

1072

Negative

2

25

Positive

4

F

5.6

ERPT

EE

None

Yes

4.5

74

Positive

2

10

Negative

5

M

6.4

ERPT

CD-Like

WS4

No

3.7

130

Negative

3

15

Negative

6

F

8.6

ERPT

CD-Like

None

No

7.3

1710

Positive

3

55

Negative

7

M

9.8

ERPT

CD-Like

CAKUT

No

8.3

1406

Positive

2

25

Positive

8

M

16.4

ERPT

CD-Like

None

No

15.5

590

Negative

2

5

Negative

9

M

17.1

Duhamel

CD-Like

None

No

16.2

1200

Positive

3

10

Positive

10

M

19.1

ERPT

CD-Like

None

Yes

17.0

823

Positive

3

17,5

Negative

11

M

22,1

Swenson

CD-Like

None

No

18.4

379

Positive

0

15

Positive

12

M

22.6

Duhamel

CD-Like

None

N.A.

21.7

83

Positive

2

20

Positive

13

M

23.8

ERPT

CD-Like

None

N.A.

14.7

366

Negative

2

15

Positive

14

M

24.1

Lester-Martin

CD-Like

None

No

21.8

318

Negative

3

20

Positive

  1. Legend – ID = Identification; M = Male; F = Female; P-T = Pull-Through; FC = Fecal Calprotectine; OFB = Occult Fecal Blood; SEMA-CD = Simplified Endoscopic Mucosal Assessment for Crohn’s Disease; PCDAI = Pediatric Crohn Disease Activity Index; HAEC = Hirschsprung Associated Enterocolitis; CD-Like = Crohn-Like; EE = Eosinophilic Enteritis; ERPT = Endorectal Pull-Through; CAKUT = Congenital Anomalies of the Kidney and Urinary Tract; WS4 = Waardenburg-Saha type 4