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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: A unicentric cross-sectional observational study on chronic intestinal inflammation in total colonic aganglionosis: beware of an underestimated condition

Fig. 4

- Bray-Curtis index to compare Cases and Controls or Caregiver-Cases and Caregiver-Controls. The PerMANOVA F-value is the test statistic used in this analysis to determine if there is a significant difference in community composition between groups. A high F-value indicates a big difference between the groups being compared, while a low F-value suggests that the groups are similar. A higher R-squared value is a strong predictor of differences between the groups. In summary, a F-value of 3.1194, R-squared of 0.11093, and a p-value of 0.007 found for TCSA patients microbiomes (Cases versus Controls on the left-hand side) suggest that there is a significant difference between the groups being compared. The F-value of 0.69544, R-squared of 0.033604, and a p-value of 0.687 typical of Caregiver comparisons suggest that there is no significant difference between Caregiver-Cases and Caregiver-Controls. Numbers inside square brackets indicate the number of individuals in each group

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