Fig. 3

Upper left quadrant - Relative abundance of phyla distribution of the microbiome of Care Givers with numbers inside square brackets indicating the number of individuals in each group

Lower right quadrant - Phyla analysis was performed on the TCSA patients microbiome grouped in Cases (with inflammation, TCSA-Cases) or Controls (without inflammation, TCSA-Controls). Numbers inside square brackets indicate the number of individuals in each group. Of note, some stools samples did not pass the internal quality control thus reducing the total number of patients in each group. In each panel, the list indicating the values of the differential abundance for each phylum between cases and controls is shown on the right. On the bottom, the right (Δ%) indicates the differential abundances between TCSA-Cases compared to TCSA-Controls green background, an increase in % abundance the red background, showed a decrease in % in TCSA-Cases.