Table 2 Baseline laboratory test information
Variables | All (n = 39) | Decreased oxygen saturation (n = 12) | Non decreased oxygen saturation (n = 27) | P value |
|---|---|---|---|---|
Arterial blood gas | ||||
pH | 7.41 ± 0.02 | 7.41 ± 0.03 | 7.41 ± 0.02 | 0.351 |
PaCO2 (mmHg) | 37.56 ± 3.11 | 37.92 ± 2.35 | 37.40 ± 3.42 | 0.639 |
PaO2 (mmHg) | 82.80 ± 13.50 | 74.50 ± 13.61 | 86.49 ± 11.92 | 0.009 |
SaO2 (%) | 96.5 (95.3, 97.7) | 95.4 (93.4, 97.7) | 96.5 (95.7, 97.7) | 0.245 |
A-aDO2 (mmHg) | 21.8 (9.6, 31.2) | 26.8 (16.0, 42.9) | 21.8 (8.9, 27.7) | 0.159 |
HCO3− (mmol/L) | 23.04 ± 1.85 | 23.48 ± 1.62 | 22.85 ± 1.94 | 0.339 |
Serology | ||||
HGB (g/L) | 158.36 ± 17.77 | 155.25 ± 21.39 | 159.74 ± 16.18 | 0.474 |
RBC# (× 1012/L) | 5.21 ± 0.61 | 5.10 ± 0.82 | 5.26 ± 0.51 | 0.456 |
HCT (%) | 45.65 ± 4.76 | 44.78 ± 6.00 | 46.04 ± 4.17 | 0.454 |
CEA (ng/ml) | 4.00 (2.43, 7.60) | 4.00 (2.29, 20.40) | 3.90 (2.43, 7.30) | 0.298 |
Cyfra21-1 (ng/ml) | 4.60 (2.60, 9.50) | 7.05 (4.00, 11.70) | 3.60 (2.30, 7.52) | 0.072 |
LDH (U/L) | 243 (204, 350) | 298 (234, 377) | 218 (197, 309) | 0.037 |
Pulmonary function | ||||
FEV1 pred (%) | 88.0 (75.5, 99.2) | 90.0 (67.0, 104.7) | 88.0 (77.0, 98.0) | 0.799 |
FVC pred (%) | 91.0 (77.0, 101.0) | 86.0 (68.3, 105.5) | 95.0 (78.0,101.0) | 0.753 |
FEV1/FVC (%) | 81.5 (77.9, 87.0) | 83.6 (81.1, 87.8) | 80.3 (76.8, 86.8) | 0.221 |
TLC pred (%) | 85.0 (73.0, 94.0) | 83.9 (65.7, 103.7) | 85.0 (77.0, 94.0) | 0.799 |
RV pred (%) | 86.0 (71.0, 99.0) | 91.0 (73.6, 105.8) | 85.0 (68.5, 99.0) | 0.822 |
DLCO pred (%) | 68.3 (52.1, 81.8) | 63.3 (44.9, 83.8) | 69.6 (63.2, 80.5) | 0.284 |
DLCO/VA pred (%) | 83.8 (75.4, 97.4) | 77.0 (74.3, 93.6) | 89.5 (78.2, 97.4) | 0.036 |
6MWD (m) | 512 (463, 570) | 464 (406, 538) | 532 (470, 575) | 0.028 |
Borg at the end of 6MWD | 1 (0, 2) | 1 (0, 3) | 0 (0, 2) | 0.538 |
SGRQ | ||||
Symptom | 28 (12, 47) | 43 (27, 69) | 24 (9, 36) | 0.010 |
Activity | 29 (17, 47) | 56 (23, 82) | 23 (6, 36) | 0.005 |
Impact | 14 (1, 43) | 40 (13, 56) | 9 (0, 23) | 0.022 |
Total | 21 (9, 51) | 46 (20, 64) | 19 (8, 26) | 0.009 |
DSS | 0.017 | |||
1 | 13 (33.3%) | 1 (8.3%) | 12 (44.4%) | |
2 | 20 (51.3%) | 7 (58.3%) | 13 (48.1%) | |
≥ 3 | 6 (15.4%) | 4 (33.3%) | 2 (7.4%) | |