Table 1 Demographic data for patients with SCA3 and control subjects
From: A pilot study: handgrip as a predictor in the disease progression of SCA3
Control | SCA3 | P value | |
|---|---|---|---|
Case number | 36 | 31 | |
Male (%) | 22 (61.1%) | 19 (61.3%) | 0.988 |
Age (years) | 47.0 (32.0–53.5) | 49.0 (40.0–55.0) | 0.517 |
BMI (kg/m2) | 23.6 (21.8–25.6) | 21.5 (19.5–25.5) | 0.043* |
Handgrip strength (kg) | 40.7(27.1–49.3) | 24.3 (19.2–38.2) | < 0.001* |
Handgrip strength (kg)/BMI (kg/m2) | 1.38 (1.11–1.79) | 1.19 (0.95–1.55) | < 0.001* |
Disease status | |||
The age of onset (years old) | N/A | 36 (32–45) | |
Duration (years) | N/A | 10 (5–12) | |
CAG repeat count | N/A | 71.0 (69.0–74.0) | |
SARA | N/A | 15.0 (8.5–21.0) | |
Plasma | |||
NfL (pg/mL) | 6.35 (4.22–7.63) | 28.01 (20.65–32.75) | < 0.001* |