Table 5 FAZ and VAD in Fabry disease patients with normal or altered enzyme activity
|  | Normal GLA activity (n = 10); mean ± SD | Decreased GLA activity (n = 38); mean ± SD | p value | Normal lysoGb3 activity (n = 28); mean ± SD | Increased lysoGb3 activity (n = 40); mean ± SD | p value |
|---|---|---|---|---|---|---|
FAZ area (mm2) | ||||||
Full thickness | 0.18 ± 0.07 | 0.24 ± 0.09 | 0.037 | 0.25 ± 0.13 | 0.23 ± 0.08 | 0.950 |
SVP | 0.33 ± 0.10 | 0.35 ± 0.12 | 0.736 | 0.37 ± 0.15 | 0.36 ± 0.11 | 0.822 |
ICP | 0.15 ± 0.08 | 0.22 ± 0.09 | 0.026 | 0.22 ± 0.14 | 0.22 ± 0.08 | 0.324 |
DCP | 0.33 ± 0.10 | 0.36 ± 0.14 | 0.644 | 0.41 ± 0.22 | 0.38 ± 0.10 | 0.373 |
VAD (%) | ||||||
SVP | 52.71 ± 7.70 | 51.08 ± 10.33 | 0.556 | 46.43 ± 13.76 | 50.41 ± 8.80 | 0.247 |
ICP | 31.36 ± 4.84 | 29.57 ± 7.82 | 0.644 | 27.00 ± 8.38 | 30.69 ± 6.47 | 0.065 |
DCP | 37.10 ± 6.51 | 32.45 ± 8.28 | 0.120 | 28.63 ± 9.76 | 34.35 ± 7.13 | 0.015 |