Correlation of retinal vascular characteristics with laboratory and ocular findings in Fabry disease: exploring ocular diagnostic biomarkers

Table 4 FAZ and VAD in patients with and without vascular tortuosity compared to controls

	FD eyes with vascular tortuosity (n = 20); mean ± SD	FD eyes without vascular tortuosity (n = 54–56); mean ± SD	Controls (n = 48); mean ± SD	p value
FAZ area (mm²)
Full thickness	0.24 ± 0.08	0.24 ± 0.11	0.25 ± 0.07	0.378
SVP	0.37 ± 0.10	0.36 ± 0.13	0.35 ± 0.08	0.812
ICP	0.22 ± 0.09	0.21 ± 0.11	0.24 ± 0.069	0.214
DCP	0.37 ± 0.11	0.41 ± 0.21	0.36 ± 0.07	0.829
VAD (%)
SVP	50.15 ± 9.05^a	49.08 ± 11.71^b	26.51 ± 6.18^ab	< 0.001
ICP	32.18 ± 5.62^a	28.64 ± 7.82^b	20.17 ± 4.38^ab	< 0.001
DCP	33.75 ± 6.78^a	31.71 ± 9.42^b	21.71 ± 5.08^ab	< 0.001

Kruskal Wallis Test, Bold indicates statistical significance (p < 0.05)
^ap < 0.03 using Mann–Whitney U Test between eyes with vascular tortuosity and controls
^bp < 0.001 using Mann–Whitney U Test between eyes without vascular tortuosity and controls

ISSN: 1750-1172