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Table 3 FAZ and VAD in patients with and without cornea verticillata compared to controls

From: Correlation of retinal vascular characteristics with laboratory and ocular findings in Fabry disease: exploring ocular diagnostic biomarkers

 

FD eyes with cornea verticillata (n = 40–42); mean ± SD

FD eyes without cornea verticillata (n = 34); mean ± SD

Controls (n = 48); mean ± SD

p value

FAZ area (mm2)

Full thickness

0.22 ± 0.09

0.26 ± 0.11

0.25 ± 0.07

0.196

SVP

0.35 ± 0.11

0.38 ± 0.13b

0.35 ± 0.08b

0.780

ICP

0.19 ± 0.10

0.24 ± 0.11

0.24 ± 0.069

0.142

DCP

0.38 ± 0.10a

0.41 ± 0.21

0.36 ± 0.07a

0.677

VAD (%)

SVP

50.95 ± 8.74a

47.41 ± 13.19b

26.51 ± 6.18ab

< 0.001

ICP

31.70 ± 6.63ac

28.94 ± 7.62bc

20.17 ± 4.38ab

< 0.001

DCP

35.30 ± 6.99ac

28.47 ± 9.44bc

21.71 ± 5.08ab

< 0.001

  1. Kruskal Wallis Test, Bold indicates statistical significance (p < 0.05)
  2. a p < 0.01 using Mann–Whitney U Test between eyes with cornea verticillata and controls
  3. b p < 0.05 using Mann–Whitney U Test between eyes without cornea verticillata and controls
  4. c p < 0.01 using Mann–Whitney U Test between eyes with and without cornea verticillata