Derivation and validation of diagnostic models for myocardial fibrosis in duchenne muscular dystrophy: assessed by multi-parameter cardiovascular magnetic resonance

Table 2 The difference of CMR parameters between LGE + and LGE − DMD patients

	DMD LGE + N = 45	DMD LGE− N = 51	P value
*left ventricle structure and function*
SV	45.11 ± 12.31	43.00 ± 15.80	0.164
CO	4.35 ± 1.24	4.02 ± 1.11	0.288
EF, %	58.09 ± 8.81	62.26 ± 6.25	0.008**
EDV, ml	77.57 ± 17.05	68.65 ± 22.06	0.002**
ESV, ml	32.46 ± 9.92	25.65 ± 8.30	＜0.001**
LV mass, g	41.76 ± 9.59	38.83 ± 15.53	0.022*
LV remodeling index	0.54 ± 0.08	0.57 ± 0.13	0.316
LVGFI	47.98 ± 9.63	51.20 ± 7.10	0.043*
*Tissue characterization*
Global Native T1, ms	1304.02 ± 62.35	1271.02 ± 46.12	0.001**
T2, ms	36.52 ± 2.05	36.24 ± 3.13	0.602
*Strain*
PS-Radial (%)	29.57 ± 4.07	31.37 ± 4.45	0.043*
PS-Circumferential (%)	−18.57 ± 1.95	−19.79 ± 3.07	0.021*
PS-Longitudinal (%)	−14.93 ± 2.52	−16.43 ± 2.39	0.004**

*p＜0.05
** p＜0.01
Values are presented as mean ± standard deviation
LVGFI = {LVSV/[(LVEDV + LVESV)/2+(LV mass/1.05)]}*100, LV remodeling index, LV mass/LVEDV; PS, peak strain

ISSN: 1750-1172