From: The improvement of motor symptoms in Huntington’s disease during cariprazine treatment
P1 | P2 | P3 | P5 | P6 | P7 | P8 | P9 | P10 | P11 | P12 | P13 | P14 | P15 | P16 | |||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | BL | W8 | W12 | |
Hand movements | 0 | 0 | 0 | 7 | 5 | 6 | 8 | 8 | 8 | 3 | 2 | 2 | 18 | 15 | 17 | 2 | 1 | 1 | 7 | 4 | 3 | 11 | 11 | 9 | 9 | 8 | 7 | 13 | 17 | 16 | 7 | 6 | 6 | 9 | 7 | 6 | 12 | 11 | 7 | 5 | 4 | 2 | 0 | 0 | 0 |
Chorea | 8 | 8 | 6 | 13 | 8 | 7 | 9 | 9 | 9 | 0 | 0 | 0 | 20 | 7 | 6 | 0 | 0 | 0 | 6 | 3 | 0 | 16 | 13 | 8 | 12 | 7 | 7 | 20 | 16 | 11 | 11 | 4 | 5 | 18 | 10 | 7 | 18 | 14 | 11 | 5 | 6 | 1 | 5 | 0 | 0 |
Gait/balance | 0 | 0 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 6 | 6 | 8 | 2 | 0 | 0 | 0 | 1 | 1 | 9 | 7 | 7 | 5 | 4 | 4 | 6 | 7 | 7 | 2 | 3 | 3 | 5 | 3 | 3 | 9 | 3 | 4 | 2 | 2 | 1 | 1 | 1 | 1 |
Oropharyngeal | 1 | 1 | 1 | 4 | 4 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 4 | 4 | 4 | 0 | 0 | 0 | 1 | 1 | 1 | 3 | 3 | 3 | 3 | 2 | 2 | 7 | 5 | 5 | 1 | 1 | 1 | 3 | 2 | 2 | 4 | 3 | 4 | 2 | 1 | 0 | 0 | 0 | 0 |
Eye movements | 0 | 0 | 0 | 4 | 2 | 0 | 2 | 2 | 2 | 0 | 0 | 0 | 12 | 12 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 8 | 6 | 6 | 4 | 0 | 12 | 10 | 10 | 4 | 2 | 4 | 10 | 6 | 7 | 14 | 6 | 2 | 4 | 2 | 1 | 6 | 0 | 0 |
Rigidity/bradykinesia | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 4 | 4 | 4 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 2 | 5 | 1 | 1 | 1 | 3 | 3 | 3 | 1 | 1 | 1 | 1 | 2 | 2 | 5 | 3 | 2 | 3 | 1 | 1 | 1 | 0 | 0 |
Dystonia | 2 | 2 | 0 | 1 | 1 | 0 | 5 | 5 | 5 | 0 | 0 | 0 | 7 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 0 | 0 | 8 | 4 | 1 | 0 | 0 | 0 | 7 | 0 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |