Fig. 6From: HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunctionHDAC5 regulates MEF2A expression by influencing the ERK/EGR1 signaling pathwayVentricular remodeling induces cytoplasm translocation of HDAC5. Inhibition of ERK/EGR1 by HDAC5 results in a marked upregulation of MEF2A, which consequently contributes to the promotion of TAC-induced ventricular remodeling and Ang II-induced hypertrophy in H9C2 cellsBack to article page