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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction

Fig. 4

LMK235 reverses TAC and Ang II induced HDAC5 expression increase and cytoplasmic translocation

(A-C) Western blot results and statistical analysis of HDAC5 and MEF2A expression in mice (n = 3 for each group). (D) Representative images of immunohistochemical staining of HDAC5 in each group. Scale bar, 50 μm. (E-G) Western blot results and statistical analysis of HDAC5 and MEF2A expression in H9C2 cells (n = 3 for each group). (H) Representative images of immunofluorescence staining of HDAC5 in H9C2 cells in each group. Scale bar, 50 μm. Data are presented as means ± SD, *P < 0.05; **P < 0.01

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