Fig. 1
From: HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction
Upregulation of HDAC5 in in ventricular remodeling of TAC mice and H9C2 cells exposed to Ang II
(A-B) Representative Western blots and quantification showing HDAC5 levels in sham or TAC mice (n = 6 in each group). (C) Representative images of immunofluorescence staining of HDAC5 (red), c-TNT (green), and DAPI (blue) in the ventricular remodeling zone of mouse hearts in the sham group and 14 days after TAC. c-TNT: cardiomyocyte marker. Scale bar, 50 μm. (D-E) Representative Western blots and quantification showing HDAC5 levels in H9C2 cells in each group (n = 6 in each group). (F-G) Representative images of immunofluorescence staining and fluorescence intensity of HDAC5 in H9C2 cells in each group. Scale bar, 50 μm. n > 10 in each group. Data are presented as means ± SD, **P < 0.01