Table 1 Comparison of biochemical data of patients with late-onset cblCdefect in blood and urine before and after treatment
From: Late-onset cblC defect: clinical, biochemical and molecular analysis
|  | C3(µmol/L) | C3/C2 | Methymalonic acid (mmol/mol cr) | MCA (mmol/mol cr) | HCY(µmol/L) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
n | Median (range) | n | Median (range) | n | Median (range) | n | Median (range) | n | Median (range) | |
BEFORE TREATMENT | 63 | 6.61 (1.88–35.44) | 64 | 0.52 (0.11–2.68) | 60 | 94.45 (5.50-845.10) | 54 | 1.63 (0.00-16.61) | 72 | 100.00 (36.10-635.60) |
AFTER TREATMENT | 63 | 3.20 (0.96–12.29) | 64 | 0.16 (0.03–0.61) | 60 | 6.32 (0.00-78.66) | 54 | 0.39 (0.00-3.63) | 72 | 39.00 (1.37–84.60) |
P VALUE | ＜0.001 | ＜0.001 | ＜0.001 | ＜0.001 | ＜0.001 | |||||
REFERENCE RANGE | 0.40-4.00 | 0.03–0.20 | 0.00–4.00 | 0.00-0.70 | <15.00 | |||||